Journal article
Life course BMI trajectories from childhood to mid-adulthood are differentially associated with anxiety and depression outcomes in middle age
C Gallagher, J Pirkis, KA Lambert, JL Perret, GB Ali, CJ Lodge, G Bowatte, GS Hamilton, MC Matheson, DS Bui, MJ Abramson, EH Walters, SC Dharmage, B Erbas
International Journal of Obesity | Published : 2023
Abstract
Background/Objective: Obesity is a risk factor for multimorbidity, including depression and possibly anxiety. However, it is currently unclear how patterns of change in BMI over the life course differentially influence the magnitude in risk of depression and anxiety in mid-adulthood. We aimed to examine associations between BMI trajectories from childhood to adulthood and the risk of depression and anxiety in middle age. Methods: In the Tasmanian Longitudinal Health Study (n = 2416), five distinct BMI trajectories were previously defined from age 5 to 45 years using group-based modelling. At age 53, current depression and anxiety were assessed using the Patient Health Questionnaire and the G..
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Awarded by University of Melbourne
Funding Acknowledgements
We acknowledge the TAHS study participants and previous investigators. We thank Prof. Mark Jenkins, Centre for Epidemiology and Biostatistics, The University of Melbourne, Victoria, a TAHS investigator, but not a co-author of this manuscript, for his assistance with obtaining funds and data collection. We also acknowledge all the respiratory scientists who collected data in the lung function laboratories of Tasmania, Victoria, Queensland, South Australia, Western Australia and New South Wales; the research interviewers, data entry operators and research officers. Finally, we thank the Archives Office of Tasmania for providing data from the 1968 TAHS questionnaires. This study was supported by the National Health and Medical Research Council (NHMRC) of Australia under NHMRC project grant scheme (299901, 1021275) and NHMRC European collaborative grant scheme (1101313) as part of Ageing Lungs in European Cohorts funded by the European Union's Horizon 2020 research and innovation programme (grant agreement 633212); The University of Melbourne; Clifford Craig Medical Research Trust of Tasmania; the Victorian, Queensland & Tasmanian Asthma Foundations; The Royal Hobart Hospital; Helen MacPherson Smith Trust; and GlaxoSmithKline. We would also like to acknowledge the contributions of the Australian Government Research Training Program Scholarship in supporting Claire Gallagher's doctoral research.Open Access funding enabled and organized by CAUL and its Member Institutions.